Author

Adam J. Funk

University of Toledo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Robert Erne McCullumsmithiD· 4 shared Jarek MelleriD· 3 shared Amy J. RamseyiD· 2 shared James K. ReigleiD· 2 shared Rawan S. Alnafisah· 2 shared Sinead Marie O'DonovaniD· 2 shared Ali SalahpouriD· 1 shared Behrouz ShamsaeiiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersNeuroscience

Robert Erne McCullumsmithORCID

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4 papers

Recent·Most cited

Pharmacological impacts on schizophrenia functional analysis: a postmortem proteome study.

Rawan S. Alnafisah, James K. Reigle, Sinead Marie O'Donovan, Adam J. Funk, Jarek Meller, Robert Erne McCullumsmith, Rammohan Shukla

This study analyzes the proteomic changes in schizophrenia using postmortem brain samples and shows how antipsychotic drugs modulate these changes across multiple biological levels.

bioRxiv · Oct 26, 2021 · PreprintNeuroscience

Region-Specific PSD-95 Interactomes Contribute to Functional Diversity of Excitatory Synapses in Human Brain.

Adam J. Funk, Guillaume Labilloy, James K. Reigle, Rawan S. Alnafisah, Michael R. Heaven, Rosalinda C. Roberts, Behrouz Shamsaei, Kenneth D. Greis, Jarek Meller, Robert Erne McCullumsmith

This study identifies region-specific PSD-95 interactomes in human brain regions and links them to potential drug targets using bioinformatics and perturbagen databases.

bioRxiv · May 4, 2020 · PreprintNeuroscience

Connectivity analyses of bioenergetic changes in schizophrenia: Identification of novel treatments

Courtney R. Sullivan, Catharine A. Mielnik, Sinead Marie O'Donovan, Adam J. Funk, Eduard Bentea, Erica A. K. DePasquale, Khaled Alganem, Zhexing Wen, Vahram H. Haroutunian, Pavel Katsel, Amy J. Ramsey, Jarek Meller, Robert Erne McCullumsmith

The paper identifies PPAR agonists as potential treatments for schizophrenia by analyzing bioenergetic changes in the DLPFC using bioinformatics and experimental validation.

Molecular Neurobiology · Oct 18, 2018Peer-reviewedNeuroscience

Consequences Of NMDA Receptor Deficiency Can Be Rescued In The Adult Brain

Catharine A. Mielnik, Mary A. Binko, Yuxiao Chen, Adam J. Funk, Emily M. Johansson, Katheron Intson, Nirunthan Sivananthan, Rehnuma Islam, Marija Milenkovic, Wendy Horsfall, Ruth A. Ross, Laurent Groc, Ali Salahpour, Robert Erne McCullumsmith, Shreejoy J. Tripathy, , Amy J. Ramsey

This study shows that restoring NMDAR function in adult mice with congenital NMDAR deficiency improves cognitive behaviors, suggesting potential for adult treatment of related disorders.

Molecular Psychiatry · Jan 1, 2018Peer-reviewedNeuroscience