Author

Elena Siakaeva

Essen University HospitalORCID 0000-0002-5607-2033Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Agnieszka BędzińskaiD· 1 shared Aneta ZebrowskaiD· 1 shared Basant Kumar ThakuriD· 1 shared Bernd GiebeliD· 1 shared Bettina BudeusiD· 1 shared Cornelius H. L. KürteniD· 1 shared Damian Robert SojkaiD· 1 shared Daniel FochtmaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Agnieszka BędzińskaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

CITE-seq of murine bone marrow plasmacytoid dendritic cells and haematopoietic progenitor cells in sepsis

Johannes Andreas Korfhage, Elena Siakaeva, Mahamudul Hasan Bhuyan, Bettina Budeus, Dimitris Ttoouli, Tobias Lautwein, Stefanie B. Flohé, Stefanie Scheu

The paper provides CITE-seq data of bone marrow cells from septic and sham mice to study transcriptional and surface marker changes in sepsis.

bioRxiv · Jul 21, 2026 · PreprintImmunology

Serpins A1/A3 within tumor-derived extracellular vesicles support pro-tumoral bias of neutrophils in cancer

Maksim Domnich, Ekaterina Pylaeva, Elena Siakaeva, Nastassia Kabankova, Agnieszka Będzińska, Damian Robert Sojka, Aneta Zebrowska, Marta Gawin, Maren Soldierer, Malwina Rist, Daniel Fochtman, Irem Ozel, Bernd Giebel, Iris Helfrich, Ilona Thiel, , Jadwiga Jabłońska

This study shows tumor-derived extracellular vesicles containing serpins A1/A3 reprogram neutrophils to support tumor growth by extending their lifespan and suppressing CD8 T cells.

bioRxiv · Mar 6, 2025 · PreprintCancer Biology