Author

Florian E.C. Blanc

Lyon 1 UniversitéORCID 0000-0002-0762-0478Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:virus· 1

Frequent Co-Authors

Andre SchwarziD· 1 shared Beata TuroňováiD· 1 shared Christoph SchürmanniD· 1 shared Cindy HörneriD· 1 shared Florence GuillièreiD· 1 shared Ger van ZandbergeniD· 1 shared Gerhard HummeriD· 1 shared Jacomina Krijnse LockeriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Andre SchwarzORCID

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2 papers

Recent·Most cited

Metadynamics Simulations meet Ligand Design for the Reversible Inhibition of Human Peroxiredoxin 5

Laura Troussicot, Florian E.C. Blanc, Yoann Pascal, Sébastien Vidal, Jean‐Marc Lancelin, Florence Guillière

The paper uses metadynamics simulations to design improved ligands for human peroxiredoxin 5 by modifying a single heavy atom in an initial hit.

ACS Omega · Jul 10, 2026Peer-reviewedBiochemistry

In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges

Beata Turoňová, Mateusz Sikora, Christoph Schürmann, Wim J. H. Hagen, Sonja Welsch, Florian E.C. Blanc, Sören von Bülow, Michael Gecht, Katrin Bagola, Cindy Hörner, Ger van Zandbergen, Jonathan J. M. Landry, Nayara Trevisan Doimo de Azevedo, Shyamal Mosalaganti, Andre Schwarz, , Martin Beck

This study uses cryo electron tomography and simulations to analyze the structure of SARS-CoV-2 spike protein in situ, revealing three hinges in the stalk domain that enable orientational flexibility.

Science · Aug 18, 2020Peer-reviewedMolecular Biology