Author

Jingzhou Hao

Boston Children's HospitalORCID 0000-0002-0787-5980Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Taekjip HaiD· 2 shared Aakash BasuiD· 1 shared Aleksei AksimentieviD· 1 shared Andrew R. PopchockiD· 1 shared Brandon K. WaltheriD· 1 shared Charles L. AsburyiD· 1 shared Dylan J. Hedman· 1 shared Emily Winther SørenseniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Taekjip HaORCID

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2 papers

Recent·Most cited

Chromatin boundary permeability is controlled by CTCF conformational ensembles

Sergei Rudnizky, Peter J Murray, Emily Winther Sørensen, Theo J. R. Koenig, Sushil Pangeni, Raquel Merino‐Urteaga, Hemani Chhabra, Laura Caccianini, Iain F. Davidson, Manuel Osorio‐Valeriano, Paul W. Hook, Paul Meneses, Jingzhou Hao, Jasmin S. Zarb, Nikos S. Hatzakis, , Taekjip Ha

The paper shows CTCF controls chromatin boundary permeability through a dynamic conformational ensemble, not static occupancy, influencing cohesin capture probabilities.

bioRxiv · Nov 25, 2025 · PreprintBiophysics

Probing mechanical selection in diverse eukaryotic genomes through accurate prediction of 3D DNA mechanics

Jonghan Park, Galina Prokopchuk, Andrew R. Popchock, Jingzhou Hao, Ting-Wei Liao, S. Betty Yan, Dylan J. Hedman, Joshua Donald Larson, Brandon K. Walther, Nicole A. Becker, Aakash Basu, Louis James Maher III, Richard John Wheeler, Charles L. Asbury, Sue Biggins, , Taekjip Ha

This paper develops a computational model to predict DNA mechanics from sequence, revealing mechanical selection in diverse eukaryotes and identifying extreme DNA mechanics in nature.

bioRxiv · Dec 22, 2024 · PreprintBiophysics