Author

Hao Fan

Agency for Science, Technology and ResearchORCID 0000-0002-0822-1639Unclaimed ORCID profile · follow to get notified of new preprints

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Hao Fan2 papers · Agency for Science, Technology and Research

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chaitanya Kumar JaladankiiD· 2 shared Adelaide Herman· 1 shared Bo LiuiD· 1 shared Braden PateiD· 1 shared Chong GaoiD· 1 shared Christina L. L. ChaiiD· 1 shared Christoph BudjaniD· 1 shared Claire Shao· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Chaitanya Kumar JaladankiORCID

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2 papers

Recent·Most cited

Evaluating Molecular Docking Programs for RNA-Targeted Ligand Screening: Influence of Binding Modes and Ligand Types

Kai‐Chen Wang, Louis DeFalco, Chaitanya Kumar Jaladanki, Roland G. Huber, Christina L. L. Chai, Hao Fan

This study evaluates three docking programs for RNA-ligand screening, finding similar overall performance but differences across RNA classes and chemotypes, suggesting tailored scoring strategies could improve virtual screening.

Journal of Chemical Information and Modeling · May 12, 2026Peer-reviewedBioinformatics

Discovery of A Small Molecule non-IMiD Degrader of ZBTB7A for the Treatment of β-hemoglobinopathies

Jun Liu, Ziyang Shen, Shin‐Young Park, Yanhua Dong, Na Yu, Jing Zeng, Hannah Lee, Braden Pate, Sophia Adamia, Kim Vanuytsel, Junyan Zhang, Shang-Chuen Wu, Adelaide Herman, Shiva Moein, Wenhui Liu, , Li Chai

This paper discovers and characterizes SH6, a small molecule degrader of ZBTB7A that increases fetal hemoglobin expression in erythroid cells and shows therapeutic potential for β-hemoglobinopathies.

bioRxiv · Sep 17, 2025 · PreprintCell Biology