Kurt Højlund

Mitochondrial cristae density is increased following high-intensity interval training in patients with type 2 diabetes

This study finds that high-intensity interval training increases mitochondrial cristae density in type 2 diabetes patients, with no baseline differences in cristae density compared to other groups.

Transglutaminase 2 predicts parasitic worm-mediated protection against hepatic steatosis in obese mice

This study identifies TGM2 as a predictive marker of hepatic steatosis improvement in obese mice infected with H. p. bakeri, showing its role in type 2 immune responses and potential therapeutic applications.

Increased contact between lipid droplets and mitochondria in skeletal muscles of male elite endurance athletes

This study finds that male elite endurance athletes have greater lipid droplet-mitochondria contact in skeletal muscle compared to recreationally active individuals, linked to higher organelle densities and specific size-related associations.

The mitochondrial mRNA stabilizing protein, SLIRP, regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms

This study identifies SLIRP as a mitochondrial mRNA stabilizing protein that regulates mitochondrial structure and respiration in skeletal muscle, with exercise improving mitochondrial function through increased mitoribosome capacity.