Phosphoregulated SMCR8-FIP200 interaction connects the ALS/FTD-linked C9orf72 complex to autophagy initiation and mitochondrial quality control
Jian Wang, Colin T. Davis, Simone Kunzelmann…·Anne Schreiber
Author
The Francis Crick InstituteORCID 0000-0002-0930-2860Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Jian Wang, Colin T. Davis, Simone Kunzelmann…·Anne Schreiber
Wenxin Zhang, Thomas Litschel, Rocco D’Antuono…·Sharon A. Tooze
This study uses in vitro reconstitution to investigate ATG8 protein localization and cargo recruitment on phagophore membranes, revealing their roles in membrane expansion and bending.
Lewis Timimi, Antoni G. Wrobel, George N. Chiduza…·Rupert C. L. Beale
This paper identifies the V1H subunit of V-ATPase as a regulator of ATG16L1 recruitment in response to pH gradient disruption, linking V-ATPase function to autophagy activation.