Author

Ai Kotani

Tokai UniversityORCID 0000-0002-0976-8687Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Kai KudoiD· 2 shared Kiyoshi AndoiD· 2 shared Masato OhtsukaiD· 2 shared Motoyuki OtsukaiD· 2 shared Ryutaro KotakiiD· 2 shared Yuji MiyatakeiD· 2 shared Akinori KanaiiD· 1 shared Atsushi Irie· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

Kai KudoORCID

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4 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedJun 1, 2026

Secreted phospholipase PLA2G12A-driven lysophospholipid signaling via lipolytic modification of extracellular vesicles facilitates pathogenic Th17 differentiation

Chika Mochizuki-Ono, Yoshitaka Taketomi, Atsushi Irie…·Makoto Murakami

This study identifies PLA2G12A's role in Th17 differentiation through lysophospholipid signaling via extracellular vesicles, showing therapeutic potential for Th17-related diseases.

6 citationstop 2%

mouseproteomics

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ImmunologyeLifePeer-reviewedJan 28, 2026

A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency

Yuji Miyatake, Takeshi Kamakura, Tomokatsu Ikawa…·Ai Kotani

The paper shows that miR-195 can rescue B cell development in EBF1-deficient progenitor cells by enabling CD19 expression and recombination processes.

DOI 10.7554/elife.101510.3

mouseexperimental assay

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Molecular BiologyGenePeer-reviewedDec 16, 2020

Expression of ERV3-1 in Leukocytes of Acute Myelogenous Leukemia Patients

So Nakagawa, M. Kawashima, Yuji Miyatake…·Ai Kotani

The paper analyzes expression of 12 retroviral-like genes in AML patients and finds ERV3-1 is highly expressed in myeloid lineage cells, potentially linked to chromosome 8 trisomy.

11 citations

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintApr 10, 2018

Identification of PTBP1 responsible for caspase dependent YRNA cleavage

Jun Ogata, Yuki Sugiura, Akinori Kanai…·Ai Kotani

The paper identifies PTBP1 as responsible for caspase-dependent YRNA cleavage during apoptosis, revealing its role in ASR biogenesis.

DOI 10.1101/298851

experimental assay

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