Author

Qijun Zhang

University of Wisconsin–MadisonORCID 0000-0002-1003-7355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 2 Genetics· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:metagenomics· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Federico E. ReyiD· 4 shared A. P. ClayiD· 1 shared Alan AttieiD· 1 shared Aldons Jake LusisiD· 1 shared Alison WongiD· 1 shared Amelia Y. M. WooiD· 1 shared Barbara B. BendliniD· 1 shared Bhavana GangwariD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

Federico E. ReyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Gut bacterial metabolite imidazole propionate potentiates Alzheimer's disease pathology

Vaibhav Vemuganti, Jea Woo Kang, Qijun Zhang, Eric R. McGregor, James R. Hilser, Ruben Aquino-Martinez, Sandra Harding, Joseph Lawrence Harpt, Katharina R. Beck, Hailey Bussan, Jessamine F. Kuehn, Yuetiva Deming, Rachel Studer, Sterling C. Johnson, Sanjay Asthana, , Federico E. Rey

This study identifies imidazole propionate as a gut bacterial metabolite linked to Alzheimer's disease pathology through human and mouse experiments.

Nature Communications · Jun 26, 2026Peer-reviewedPathology

Investigation of Bile Salt Hydrolase Activity in Human Gut Bacteria Reveals Production of Conjugated Secondary Bile Acids

Lauren N. Lucas, Jillella Mallikarjun, Lea E. Cattaneo, Bhavana Gangwar, Qijun Zhang, A. P. Clay, Robert L. Kerby, David M. Stevenson, Helen E. Blackwell, Federico E. Rey, Daniel Amador‐Noguez

This study investigates BSH activity in human gut bacteria and finds that some strains can directly dehydrogenate conjugated bile acids to produce conjugated secondary bile acids, challenging the idea that deconjugation is a prerequisite for further modifications.

Nature Communications · Feb 23, 2026Peer-reviewedMicrobiology

Phenotypic high-throughput screening identifies modulators of gut microbial choline metabolism

Amelia Y. M. Woo, Walter J. Sandoval-Espínola, Maud Bollenbach, Alison Wong, Mariko Sakanaka, Qijun Zhang, Vincent Nieto, Federico E. Rey, Emily P. Balskus

This study identifies chemical scaffolds that inhibit gut microbial choline metabolism and reduce TMAO levels in mice using phenotypic screening.

mBio · Feb 23, 2026Peer-reviewedMicrobiology

Systems genetics approach uncovers associations between host amylase locus, gut microbiome and metabolic traits in hyperlipidemic mice

Qijun Zhang, Evan R. Hutchison, Calvin Pan, Matthew F Warren, Mark P. Keller, Alan Attie, Aldons Jake Lusis, Federico E. Rey

This study identifies genetic loci linking host amylase genes to gut microbiome composition and metabolic traits in hyperlipidemic mice.

bioRxiv · Feb 28, 2024 · PreprintGenetics