Author

Ping Wu

GenentechORCID 0000-0002-1018-2907Unclaimed ORCID profile · follow to get notified of new preprints

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Ping Wu2 papers

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander W. PatapoffiD· 1 shared Alexis L. RohouiD· 1 shared Angela Oh· 1 shared Benjamin T. WaltersiD· 1 shared Christine C. JaoiD· 1 shared Christopher M. KothiD· 1 shared Christopher P. ArthuriD· 1 shared Dimitry TegunoviD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

Alexander W. PatapoffORCID

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2 papers

Recent·Most cited

Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM

Jennifer E. Kung, Matthew Camp Johnson, Dimitry Tegunov, Christine C. Jao, Ping Wu, Angela Oh, May H. Lin, Jose M. Daria, Christopher M. Koth, Christopher P. Arthur, Alexis L. Rohou, Jawahar Sudhamsu

This paper introduces Rigid-Fabs, disulfide-constrained antibody fragments that enable high-resolution cryo-EM structures of small proteins by overcoming size limitations.

Nature Communications · Sep 30, 2025Peer-reviewedBiophysics

Integrating Hydrogen Exchange with Molecular Dynamics for Improved Ligand Binding Predictions

Benjamin T. Walters, Alexander W. Patapoff, James R. Kiefer, Ping Wu, Weiru Wang

This paper introduces HX-ESP, a method combining hydrogen exchange data with molecular dynamics to predict ligand binding modes, outperforming flexible docking for conformationally flexible targets.

Journal of Chemical Information and Modeling · Jun 11, 2025Peer-reviewedBiophysics