Dimitry Tegunov

MissAlignment improves cryo-ET tilt-series alignment by training a neural network to recognize misalignment without requiring well-aligned ground truth.

This paper introduces torch-projectors, a high-performance differentiable Fourier-space projection library for PyTorch that outperforms existing implementations by 1-2 orders of magnitude.

This paper introduces Rigid-Fabs, disulfide-constrained antibody fragments that enable high-resolution cryo-EM structures of small proteins by overcoming size limitations.

The paper reports a dimeric structure of SARS-CoV-2 RdRp and suggests it may facilitate template switching during transcription.

The paper determines the in-cell architecture of a transcribing and translating expressome in Mycoplasma pneumoniae using integrative structural methods.

The paper determines the structure of the yeast RSC chromatin remodeller bound to a nucleosome, revealing mechanisms of nucleosome sliding and implications for human SWI/SNF complexes and cancer.

The paper determines the cryo-EM structure of the human core TFIIH-XPA-DNA complex, revealing how XPA and XPG switch TFIIH from a transcription factor to a DNA repair factor.