Author

Christine C. Jao

GenentechORCID 0009-0003-2597-8937Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexander LeitneriD· 1 shared Alexander S. HauseriD· 1 shared Alexis L. RohouiD· 1 shared Angela Oh· 1 shared Bettina Brokowski· 1 shared Christian RosenmundiD· 1 shared Christopher M. KothiD· 1 shared Christopher P. ArthuriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Alexander LeitnerORCID

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2 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedSep 30, 2025

Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM

Jennifer E. Kung, Matthew Camp Johnson, Dimitry Tegunov…·Jawahar Sudhamsu

This paper introduces Rigid-Fabs, disulfide-constrained antibody fragments that enable high-resolution cryo-EM structures of small proteins by overcoming size limitations.

12 citations

cryo-EMexperimental assay

𝕏 PostBluesky

NeuroscienceScience AdvancesPeer-reviewedMar 14, 2025

The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins

Samuel George Usher, Estelle Toulmé, Roberta Florea…·Stephan Alexander Pless

The paper shows that SNARE complex proteins inhibit NALCN channel activity and that reducing NALCN currents promotes cell survival in syntaxin-depleted cells.

3 citations

experimental assay

𝕏 PostBluesky