Steven L. Coon

Anatomical and Molecular Characterization of the Zebrafish Meninges

This paper characterizes the zebrafish meninges using single-cell transcriptomics, identifying a novel cell type essential for brain development.

A reference induced pluripotent stem cell line for large-scale collaborative studies

The paper identifies and characterizes a reference iPSC line, KOLF2.1J, for standardized use in collaborative studies across multiple differentiation protocols and assays.

Transcriptomic heterogeneity of Sox2-expressing pituitary cells

This study uses scRNA-seq to analyze Sox2-expressing cells in rat pituitary, identifying heterogeneity in folliculostellate cells and their potential stem-like properties.

A fully automated FAIMS-DIA proteomic pipeline for high-throughput characterization of iPSC-derived neurons

The paper presents a fully automated FAIMS-DIA proteomic pipeline for iPSC-derived neurons, showing high protein identification and reproducibility, validated against single-cell RNA-Seq data.

Detection of precisely edited CRISPR/Cas9 alleles through cointroduced restriction-fragment length polymorphisms

The paper introduces TIARS, a method to detect precise CRISPR/Cas9 edits using restriction-fragment length polymorphisms, and validates it in zebrafish for atp7a gene mutations.

Neuronal Enhancers are Hotspots For DNA Single-Strand Break Repair

The paper identifies DNA single-strand breaks (SSBs) accumulating at neuronal enhancers and shows their repair involves PARP1, XRCC1, and DNA polymerase β.