Jethro Adam Herberg

Bacterial histone-like proteins released during antibiotic treatment mediate vascular injury in meningococcal sepsis.

Antibiotic treatment of meningococcal and other sepsis causative bacteria triggers the release of histone-like proteins (HLPs) that damage the endothelium and drive coagulopathy, but these effects can be neutralized by non-anticoagulant heparins or anti-HLP antibodies.

A 5-transcript signature for discriminating viral and bacterial etiology in pediatric pneumonia

The paper identifies a 5-transcript signature in blood samples that distinguishes bacterial from viral pneumonia with high accuracy.

Kawasaki Disease patient stratification and pathway analysis based on host transcriptomic and proteomic profiles

This study stratifies Kawasaki Disease patients using transcriptomic and proteomic profiles, finding KD responses resemble bacterial infections but with distinct features suggesting alternative triggers.

Viral and bacterial infection elicit distinct changes in plasma lipids in febrile children

This study identifies distinct lipidomic changes in febrile children with bacterial vs. viral infections, showing potential for metabolic biomarkers to aid in clinical diagnosis.