Xin Jin

Asymmetric cortical projections to striatal direct and indirect pathways distinctly control actions

The paper shows that corticostriatal projections to D1- and D2-SPNs are asymmetrically overlapping and that pathway-specific subcircuits control distinct behaviors.

Multiple dynamic interactions from basal ganglia direct and indirect pathways mediate action selection

This study identifies dynamic interactions between basal ganglia direct and indirect pathways in action selection using mouse models and proposes a new 'Triple-control' model.

Brain-wide Correspondence Between Neuronal Epigenomics and Long-Distance Projections

The paper links single-cell epigenomes and projection patterns of 33,034 mouse neurons to identify transcriptomic and epigenomic properties of projection cell types.

Characterization of striatal dopamine projections across striatal subregions in behavioral flexibility

This study investigates how dopamine release in different striatal regions affects behavioral flexibility using optogenetics in mice.

Nigrostriatal Dopamine Signals Sequence-Specific Action-Outcome Prediction Errors

This study shows that dopamine signals sequence-specific action-outcome prediction errors in mice during sequential instrumental actions.

Epigenomic Diversity of Cortical Projection Neurons in the Mouse Brain

The paper links epigenomic properties of cortical projection neurons to their anatomical and projection patterns using single-nucleus DNA methylation sequencing in mice.

Dynamic encoding of saccade sequences in primate frontal eye field

This study investigates how primate frontal eye field encodes sequential saccades, finding context-dependent dynamic encoding and a causal role in planning and executing saccade sequences.