Author

Kristiina M. Huttunen

University of Eastern FinlandORCID 0000-0002-1175-8517Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Janne TampioiD· 2 shared Minna SivoneniD· 2 shared Vesa‐Pekka LehtoiD· 2 shared Wujun XuiD· 2 shared Adéla KrálováiD· 1 shared Anna–Liisa LevoneniD· 1 shared Emilia HapponeniD· 1 shared Enkhzaya BatnasaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Janne TampioORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mechanical Activation of Piezo1 by Virus-like Nanospikes to Potentiate STING-driven Macrophage Reprogramming

Jiajia Wang, Minna Sivonen, Enkhzaya Batnasan, Sini Pitkänen, Janne Tampio, Adéla Králová, Minna-Mari Tervo, Leena Latonen, Anna–Liisa Levonen, Kristiina M. Huttunen, Tarja Malm, Rashid A. Giniatullin, Vesa‐Pekka Lehto, Wujun Xu

This study shows virus-like nanospikes activate Piezo1 to enhance STING signaling in macrophages, promoting M1 polarization through mechanical and inflammatory signals.

bioRxiv · Aug 9, 2026 · PreprintImmunology

Biomimetic porous silicon for rationally engineered combination therapy to induce immunogenic cell death

Silja Saarela, Emilia Happonen, Milla-Iida Laari, Minna Sivonen, Mohammed Zakir, Shaghayegh Saba, Janne Tampio, Ruixian Liu, Juha T. Klefström, Katja Pajula, Kristiina M. Huttunen, Vesa‐Pekka Lehto, Wujun Xu

This study identifies JQ1 and 45°C as optimal components for a combined chemo-photothermal therapy to induce immunogenic cell death in metastatic breast cancer.

Nanomedicine Nanotechnology Biology and Medicine · Mar 18, 2026Peer-reviewedBioengineering