Author

Christian D. Schlieker

Yale UniversityORCID 0000-0002-1237-4267Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Assay:CUT&Tag· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Brigitte S. NaughtoniD· 2 shared Julien BerroiD· 2 shared Sunanda MallikiD· 2 shared Vanessa TodorowiD· 2 shared Yuan ReniD· 2 shared Avinash Kumar· 1 shared Barbara Fujita· 1 shared C. D. MukherjeeiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Brigitte S. NaughtonORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Integrative Chemical Genetics Platform Identifies Condensate Modulators Linked to Neurological Disorders

Dylan Poch, C. D. Mukherjee, Sunanda Mallik, Vanessa Todorow, E. F. Elsiena Kuiper, Nalini Dhingra, Yulia V. Surovtseva, Christian D. Schlieker

The paper introduces a platform to identify condensate modulators linked to neurological disorders using chemical and genetic screens.

Molecular Biology of the Cell · Jul 8, 2026Peer-reviewedCell Biology

Nodal Modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation

Brigitte S. Naughton, Swapnil C. Devarkar, Vanessa Todorow, Sunanda Mallik, Stacey Oxendine, Sanjana Junnarkar, Yuan Ren, Julien Berro, Janine Kirstein, Yong Xiong, Christian D. Schlieker

This study identifies NOMO as a force-bearing ER transmembrane protein essential for muscle differentiation and ER morphology under mechanical strain.

The Journal of Cell Biology · May 31, 2025Peer-reviewedCell Biology

Genetically encoded mechano-sensors with versatile readouts and compact size

Yuan Ren, Jie Yang, Takumi Saito, Oliver Glomb, Avinash Kumar, Sayed Iman Mousavi, Brigitte S. Naughton, Christina A. de Fontnouvelle, Barbara Fujita, Zhiqun Xi, Christian D. Schlieker, Shaul Yogev, Yongli Zhang, Julien Berro

This paper introduces genetically encoded mechano-sensors using coiled coils to measure mechanical forces in vivo with diverse readouts and compact design.

bioRxiv · Jan 16, 2025 · PreprintCell Biology