Author

Jack C. Hanna

University of GlasgowORCID 0000-0002-1302-8905Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Clare R. HardingiD· 2 shared Anita A. KoshyiD· 1 shared Capucin Merlet· 1 shared Caroline BissardoniD· 1 shared E. M. Sands· 1 shared Giel G. van DooreniD· 1 shared Jaden Todd-Nelson· 1 shared Kiana Koehler· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Clare R. HardingORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Copper transport is required for metabolism and persistence of Toxoplasma gondii

Lucas Pagura, Jaden Todd-Nelson, Capucin Merlet, Jack C. Hanna, Laura Faulds, Sambamurthy Chandrasekaran, S H. Park, Kiana Koehler, Yamil Sanchez-Rosario, Michael D. L. Johnson, Caroline Bissardon, Peter Cloetens, Matthew W. Bowler, Stephen J. Fairweather, Giel G. van Dooren, , Clare R. Harding

This study identifies two copper transporters in Toxoplasma gondii and shows their roles in parasite metabolism and persistence.

bioRxiv · May 2, 2026 · PreprintCell Biology

Cryptosporidium Oocyst Wall Proteins are true oocyst wall proteins, with COWP8 functioning to hold the inner and outer layers of the oocyst wall together

Ross Bacchetti, Sarah Stevens, Leandro Lemgruber, Mariana Azevedo Gonzalez‐Oliva, E. M. Sands, Konstantinos Alexandrou, Michele Tinti, Lee Robinson, Jack C. Hanna, Simona Seizova, Peyton Goddard, Massimo Vassalli, Mattie Christine Pawlowic

The paper identifies and characterizes Cryptosporidium Oocyst Wall Proteins (COWPs), showing that COWP8 maintains the structural integrity of the oocyst wall without affecting viability or chlorination resistance.

PLoS Pathogens · Oct 23, 2025Peer-reviewedMicrobiology

Global translational and metabolic remodelling during iron deprivation in Toxoplasma gondii

Jack C. Hanna, Shikha Shikha, Megan A. Sloan, Clare R. Harding

This study investigates how Toxoplasma gondii adapts to iron deprivation through proteomic and metabolomic analyses, revealing translational repression and metabolic rewiring.

bioRxiv · Aug 11, 2025 · PreprintMicrobiology