Leandro Lemgruber

The paper discovers a new synaptic structure called the Honeycomb Synapse in the spinal cord, showing its vulnerability in ALS models.

The paper uses crosslinking mass spectrometry to map protein interactions in Toxoplasma gondii, identifying novel components of essential complexes and revealing structural diversity in mitochondrial machinery.

This paper investigates the role of fatty acid elongases (FAE) in Toxoplasma gondii type II strains, showing their importance for virulence, persistence, and lipid metabolism under stress.

Antibiotic treatment of meningococcal and other sepsis causative bacteria triggers the release of histone-like proteins (HLPs) that damage the endothelium and drive coagulopathy, but these effects can be neutralized by non-anticoagulant heparins or anti-HLP antibodies.

The paper identifies and characterizes Cryptosporidium Oocyst Wall Proteins (COWPs), showing that COWP8 maintains the structural integrity of the oocyst wall without affecting viability or chlorination resistance.

This study creates a tissue atlas of Cryptosporidium parvum infection in neonatal calves and immunocompromised mice to compare infection patterns and host-parasite interactions.

This study shows that endocytosis is essential for gliding motility in Toxoplasma gondii, as it enables retrograde membrane flow and the recycling of surface proteins.

This study shows that TbRH2A is essential for resolving R-loops and preventing DNA damage in T. brucei, with distinct roles in RNA Pol II and Pol I transcription.

This study shows that ATR kinase in Trypanosoma brucei is essential for DNA damage signaling and controls monoallelic VSG expression during antigenic variation.

This study shows Toxoplasma gondii forms stable F-actin networks in vivo, essential for replication and vesicle exchange between parasites.