James B. Rand

Transcriptional responses to chronic oxidative stress require cholinergic activation of G-protein-coupled receptor signaling

This study shows that cholinergic activation of G-protein-coupled receptor signaling is essential for transcriptional responses to chronic oxidative stress in C. elegans, linking cholinergic signaling to antioxidant defenses and neurodegenerative disease.

Systematic phenomics analysis of ASD-associated genes reveals shared functions and parallel networks underlying reversible impairments in habituation learning

This study systematically analyzes ASD-associated genes in C. elegans, identifying phenotypic relationships and reversible impairments in habituation learning.