Xueting Liu

TRACER navigates rearrangement-driven sesterterpene chemical space via multimodal enzyme-product representation learning

TRACER predicts terpene skeletal rearrangements by learning enzyme-product associations, identifying novel carbon skeletons and mechanistic insights.

Fruit trichome density outweighs cuticle thickness as the dominant barrier to postharvest water loss in tomato

This study shows that fruit trichome density is a more significant factor than cuticle thickness in determining postharvest water loss in tomatoes, as mutants with fewer trichomes had reduced water loss and longer shelf life despite thinner cuticles.

Methionine γ-lyase Traps Cofactor Pyridoxal-5'-phosphate through Specific Serine-Mediated Affinity

This study identifies a conserved serine in the C-terminal domain of MGL that mediates specific PLP binding and catalytic efficiency.

Coat protein of TCV suppresses RNA decay via ubiquitination and autophagy pathways to facilitate viral infection

This study shows that TCV's coat protein suppresses RNA decay by degrading AtDcp1 via ubiquitination and autophagy, enhancing viral infection.

Simple cloning of large natural product biosynthetic gene clusters from Streptomyces by an engineered CRISPR/Cas12a system

The paper develops a method to efficiently clone large GC-rich BGCs from Streptomyces genomes using a CRISPR/Cas12a-based system, demonstrating its effectiveness with a 87-kb BGC.