Daniel E. Gustavson

This study identifies sex-specific genetic loci and correlations for alcohol use behaviors and their comorbidities using genome-wide association studies.

The paper investigates polygenic associations between motor behaviour, neuromotor traits, and active music engagement across four cohorts, finding a link between walking pace polygenic scores and music engagement.

The paper uses genomic structural equation modeling to identify latent genetic factors underlying cortical surface area and thickness, finding genetic correlations with psychiatric disorders.

This study identifies 14 genome-wide significant loci for delay discounting in 134,935 individuals and shows genetic associations with 212 medical conditions.

The paper uses genomic structural equation modeling to partition genetic variation between behavioral disinhibition, substance use, and substance use disorder traits.

The paper investigates genetic associations between internalizing and externalizing traits and polysubstance use, finding unique genetic contributions from externalizing traits.

This study conducts a genome-wide association study to identify genetic variants linked to musical beat synchronization, finding high polygenicity with 69 significant loci and heritability estimates of 13%-16%.

This paper conducts a multivariate GWAS of AUDIT items to correct biases and identify novel genetic associations between alcohol consumption, misuse, and health outcomes.

This study uses genomic structure equation modeling to show impulsivity traits have distinct genetic factors, with urgency most linked to internalizing psychopathology.

The paper shows that poor episodic memory and semantic verbal fluency in middle-aged men predict progression to mild cognitive impairment within six years.

The paper shows that cognitive function predicts progression to Aβ-positivity, even when controlling for baseline biomarker levels, suggesting cognitive measures may identify early AD risk.

The paper shows that higher Alzheimer’s disease polygenic risk scores are linked to greater pupillary dilation during cognitive tasks in midlife, suggesting a genetic biomarker for early AD risk.

The paper examines how genetic risk for coronary heart disease interacts with Alzheimer’s genetic risk to influence mild cognitive impairment risk in a cohort of 1,209 individuals.

This study identifies 99 genetic loci associated with general cognitive function using data from 280,360 individuals, finding genes linked to brain structure and neurodegenerative disorders.