Author

Andrew J. Pickering

Koch Institute for Integrative Cancer Research At MITORCID 0000-0002-1496-7752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioengineering· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Darrell J. IrvineiD· 2 shared Ezra GordoniD· 2 shared Ivan Susin PiresiD· 2 shared Mae L. PryoriD· 2 shared Margaret M. BillingsleyiD· 2 shared Paula Therese HammondiD· 2 shared Aidan KindoppiD· 1 shared Alexander D. StonemaniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

Darrell J. IrvineORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Surface avidity of anionic polypeptide coatings target nanoparticles to cancer-associated amino acid transporters

Ivan Susin Pires, Margaret M. Billingsley, Ezra Gordon, Andrew J. Pickering, Eva Cai, Gonzalo J. Esparza, Mae L. Pryor, Alexander D. Stoneman, Aidan Kindopp, Darrell J. Irvine, Paula Therese Hammond

The paper shows that anionic polypeptide coatings on nanoparticles bind to cancer-associated amino acid transporters, enabling targeted drug delivery through electrostatic interactions and transporter clustering.

Angewandte Chemie International Edition · Dec 22, 2025Peer-reviewedBioengineering

'Target-and-release' nanoparticles for effective immunotherapy of metastatic ovarian cancer

Ivan Susin Pires, Gil Covarrubias, Victoria F. Gomerdinger, Coralie M. Backlund, Eduardo Nombera Bueno, Margaret M. Billingsley, Mae L. Pryor, Apoorv Shanker, Ezra Gordon, Shengwei Wu, Andrew J. Pickering, Mariane B. Melo, Heikyung Suh, Darrell J. Irvine, Paula Therese Hammond

This study develops IL-12-loaded nanoparticles that enhance immunotherapy for metastatic ovarian cancer by promoting T cell accumulation and sensitizing tumors to checkpoint inhibitors.

Nature Materials · Oct 31, 2025Peer-reviewedBioengineering