Author

Gil Covarrubias

Koch Institute for Integrative Cancer Research At MIT

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Apoorv ShankeriD· 2 shared Ivan Susin PiresiD· 2 shared Paula Therese HammondiD· 2 shared Victoria F. GomerdingeriD· 2 shared Aidan KindoppiD· 1 shared Alexander D. StonemaniD· 1 shared Andrea Li· 1 shared Andrew J. PickeringiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioengineering

Apoorv ShankerORCID

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2 papers

Recent·Most cited

Engineering nanoparticle surface chemistry for antigen-presenting cell targeting improves specificity and safety of TLR3 agonist cancer immunotherapy

Victoria F. Gomerdinger, Cassandra Parada, Andrea Li, Aidan Kindopp, Justin A. Kaskow, Eva Cai, Julia Treese, Ivan Susin Pires, Apoorv Shanker, Gil Covarrubias, Alexander D. Stoneman, Magalie Boucher, Paula Therese Hammond

This paper develops a nanoparticle platform to target TLR3 agonist to antigen-presenting cells, improving cancer immunotherapy safety and efficacy by reducing systemic toxicity and enhancing tumor targeting.

bioRxiv · Jun 25, 2026 · PreprintBioengineering

'Target-and-release' nanoparticles for effective immunotherapy of metastatic ovarian cancer

Ivan Susin Pires, Gil Covarrubias, Victoria F. Gomerdinger, Coralie M. Backlund, Eduardo Nombera Bueno, Margaret M. Billingsley, Mae L. Pryor, Apoorv Shanker, Ezra Gordon, Shengwei Wu, Andrew J. Pickering, Mariane B. Melo, Heikyung Suh, Darrell J. Irvine, Paula Therese Hammond

This study develops IL-12-loaded nanoparticles that enhance immunotherapy for metastatic ovarian cancer by promoting T cell accumulation and sensitizing tumors to checkpoint inhibitors.

Nature Materials · Oct 31, 2025Peer-reviewedBioengineering