Author

Simon Höfflin

Research Institute of Molecular PathologyORCID 0000-0002-1514-0992Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Achim DickmannsiD· 1 shared David HaselbachiD· 1 shared Florian AnderschiD· 1 shared Hanna L. BrunneriD· 1 shared Hannah KnaudtiD· 1 shared Harald KotischiD· 1 shared Irina GrishkovskayaiD· 1 shared Johannes A. ZuberiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Achim DickmannsORCID

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1 paper

Recent·Most cited

A multivalent adaptor mechanism drives the nuclear import of proteasomes

Hanna L. Brunner, Robert Kalis, Lorenz Grundmann, Zuzana Hodáková, Zuzana Koskova, Irina Grishkovskaya, Melanie de Almeida, Matthias Hinterndorfer, Hannah Knaudt, Simon Höfflin, Florian Andersch, Harald Kotisch, Achim Dickmanns, Sara Cuylen‐Haering, Johannes A. Zuber, David Haselbach

The paper identifies AKIRIN2 as a multivalent adaptor protein that coordinates proteasome nuclear import through a stepwise assembly of importin clusters.

Nature Communications · Feb 4, 2026Peer-reviewedMolecular Biology