Sara Cuylen‐Haering

In-cell structures visualize human pre-ribosome assembly in the nucleolus

This study visualizes human pre-ribosome assembly in nucleoli using cryogenic correlative light and electron tomography, revealing structural states and interactions.

Ki-67 shapes the nucleolus by anchoring chromatin via its amphiphilic properties

This study identifies Ki-67 as a regulator of nucleolar shape through its amphiphilic properties that anchor chromatin, linking nucleolar morphology to genome organization.

A multivalent adaptor mechanism drives the nuclear import of proteasomes

The paper identifies AKIRIN2 as a multivalent adaptor protein that coordinates proteasome nuclear import through a stepwise assembly of importin clusters.

Charge distribution of coating brush drives inter-chromosome attraction

The paper investigates how the charge distribution on Ki-67 affects RNA-mediated inter-chromosome attraction during cell division.

Unsupervised temporal consistency improvement for microscopy video segmentation with Siamese networks

The paper improves microscopy video segmentation by retraining a CNN with a Siamese network setup using unlabelled video frames.

Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription

This study shows condensin affects RNA levels by causing chromosome missegregation, not by directly regulating transcription.