Author

Hannah Knaudt

University of ViennaORCID 0009-0005-0772-9042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

David HaselbachiD· 2 shared Irina GrishkovskayaiD· 2 shared Johannes A. ZuberiD· 2 shared Robert KalisiD· 2 shared Achim DickmannsiD· 1 shared Florian AnderschiD· 1 shared Hanna L. BrunneriD· 1 shared Harald KotischiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

David HaselbachORCID

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2 papers

Recent·Most cited

A multivalent adaptor mechanism drives the nuclear import of proteasomes

Hanna L. Brunner, Robert Kalis, Lorenz Grundmann, Zuzana Hodáková, Zuzana Koskova, Irina Grishkovskaya, Melanie de Almeida, Matthias Hinterndorfer, Hannah Knaudt, Simon Höfflin, Florian Andersch, Harald Kotisch, Achim Dickmanns, Sara Cuylen‐Haering, Johannes A. Zuber, David Haselbach

The paper identifies AKIRIN2 as a multivalent adaptor protein that coordinates proteasome nuclear import through a stepwise assembly of importin clusters.

Nature Communications · Feb 4, 2026Peer-reviewedMolecular Biology

Structural basis for the ubiquitin chain recognition of the human 26S proteasome

Sascha Josef Amann, Robert Kalis, Maximilian Fottner, Hannah Knaudt, Irina Grishkovskaya, Johannes A. Zuber, Kathrin Lang, Nicholas Gene Brown, David Haselbach

The paper determines how the human 26S proteasome distinguishes between K48-linked and K11/K48-branched ubiquitin chains through structural analysis and functional studies.

bioRxiv · Apr 7, 2025 · PreprintBiochemistry