Jonathan Rodiger

FlyPredictome scores 1.5 million AlphaFold-Multimer predictions of Drosophila protein pairs with a contact-aware integrated Local Interaction Score (iLIS), yielding residue-level interfaces enriched for phenotype-associated missense alleles.

TF2TG integrates TF-DNA binding, protein-protein interactions, and transcriptomic data to identify and rank potential target genes for Drosophila transcription factors.

A Local Interaction Score (LIS), computed from AlphaFold-Multimer predicted aligned error, separates curated fly and human protein interactions from controls better than ipTM, recovering small or flexible interfaces.

Paralog Explorer identifies candidate paralogs in model organisms and provides tools for their functional analysis.

FlyPhoneDB predicts cell-cell communication in Drosophila using scRNA-seq data by calculating interaction scores between ligand-receptor pairs.

The paper develops bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquito cell lines to study gene function and disease control.

DRscDB provides a database for comparing scRNA-seq data across species, enabling searches for orthologous genes and cell type-specific expression patterns.

BioLitMine helps researchers find relevant biomedical literature by leveraging MeSH terms and gene annotations to improve search accuracy and identify co-cited genes and authors.

SNP-CRISPR is a web tool that designs CRISPR sgRNAs for SNP-containing alleles, accounting for genetic variations in non-reference genomes and across genetic backgrounds.