Nutrient-responsive and DAF-16/FoxO target H1 histone HIL-1 promotes resistance to starvation and bacterial pathogens in Caenorhabditis elegans
Kinsey Fisher, Rojin Chitrakar, L. Ryan Baugh
This study identifies HIL-1, a DAF-16/FoxO target gene, as a key mediator of starvation and bacterial pathogen resistance in C. elegans by activating immune-related genes during nutrient deprivation.