Author

Edmar R. Oliveira-Filho

University of FloridaORCID 0000-0002-1597-0830Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Arabidopsis· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Andrew D. HansoniD· 3 shared Kristen Van GelderiD· 2 shared A. Harvey MillariD· 1 shared Anuran Kumar GayeniD· 1 shared Bryan J. LeongiD· 1 shared Cătălin VoiniciuciD· 1 shared David ObeiD· 1 shared Jorge D. García-GarcíaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersSynthetic Biology

Andrew D. HansonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rethinking suicide Thi4 thiazole synthases: comparative genomic insights and pilot functional evidence

Edmar R. Oliveira-Filho, Kristen Van Gelder, David Obe, Cătălin Voiniciuc, Mark A. Wilson, Andrew D. Hanson

This paper investigates suicide Thi4 thiazole synthases, showing genomic evidence suggesting non-suicidal function and supporting this with functional experiments in E. coli.

ACS Omega · Jun 12, 2026Peer-reviewedBiochemistry

Continuous Directed Evolution of a Plant Histidinol Dehydrogenase to Extend Lifespan

Edmar R. Oliveira-Filho, Anuran Kumar Gayen, Bryan J. Leong, Katharina Belt, A. Harvey Millar, Andrew D. Hanson

This study uses directed evolution to extend the lifespan of an Arabidopsis enzyme by increasing its abundance and improving its resistance to a toxic intermediate.

bioRxiv · Jul 1, 2025 · PreprintSynthetic Biology

Directed evolution of aerotolerance in sulfide-dependent thiazole synthases

Kristen Van Gelder, Edmar R. Oliveira-Filho, Jorge D. García-García, You Hu, Steven D. Bruner, Andrew D. Hanson

This study improves the aerotolerance and activity of sulfide-dependent THI4 enzymes through directed evolution in yeast, identifying beneficial mutations that enhance their performance under aerobic conditions.

ACS Synthetic Biology · Mar 15, 2023Peer-reviewedSynthetic Biology