PhysiologyDiabetesPeer-reviewed
Gut-derived GLP-1 released by rare sugar D-allulose cooperates with insulin to activate left-sided vagal afferents and enhance insulin sensitivity
Kento Ohbayashi, Mamoru Tanida, Chikara Abe…·Yusaku Iwasaki
This paper shows that D-allulose-induced GLP-1 enhances insulin action via left-sided vagal afferents, improving glucose tolerance more effectively than GLP-1 receptor agonists in mice.
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