Author

Michaela E. Dungan

University of PennsylvaniaORCID 0000-0002-1634-9501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Bryson W. KatonaiD· 2 shared Keely A. BeyriesiD· 2 shared Ariana D. Majer· 1 shared Baron Chen· 1 shared Bhoomi Madhu· 1 shared Blake A. NiccumiD· 1 shared Chaoting ZhouiD· 1 shared Christopher J. LengneriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Bryson W. KatonaORCID

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2 papers

Recent·Most cited

MAIT cell enrichment in Lynch syndrome is associated with immune surveillance and colorectal cancer risk

Hairu Yang, Michaela E. Dungan, Bhoomi Madhu, Keely A. Beyries, Xin Wang, Robert Kilpatrick, Baron Chen, Sangmi Oh, Marissa Berkowitz, David Glenn Smith, Chaoting Zhou, Sergei B. Koralov, Jordan E. Axelrad, Christopher J. Lengner, Nicole Maloney Belle, , Ken Cadwell

The paper identifies MAIT cell enrichment in Lynch syndrome carriers without CRC, linked to immune surveillance and reduced cancer risk.

Gut · May 19, 2026Peer-reviewedImmunology

Gastric epithelium from BRCA1 and BRCA2 carriers harbors increased double-stranded DNA damage and augmented growth.

Kole H. Buckley, Michaela E. Dungan, Kevin Dinh, Gregory M. Kelly, Ryan M. Hausler, Kate E Bennett, Daniel G. Clay, Julia E Youngman, Ariana D. Majer, Keely A. Beyries, Blake A. Niccum, Sydney M. Shaffer, Tatiana A. Karakasheva, Kathryn E. Hamilton, Michael L. Kochman, , Bryson W. Katona

This study finds BRCA1 and BRCA2 carriers have increased DNA damage and growth in gastric epithelium and organoids, suggesting haploinsufficiency contributes to early gastric cancer development.

bioRxiv · Oct 1, 2025 · PreprintCancer Biology