Author

Marshall S. Horwitz

University of WashingtonORCID 0000-0002-1683-1680Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Approach:Bayesian inference· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Aaron McKennaiD· 1 shared Alison F. FederiD· 1 shared Brendan F. KohrniD· 1 shared Charles C. ValentineiD· 1 shared Desiree A. MarshalliD· 1 shared Donovan J. AndersoniD· 1 shared Elizabeth K. SchmidtiD· 1 shared Eric Quentin KonnickiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Aaron McKennaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ultra-deep duplex sequencing reveals unique features of somatic evolution in the normal tissues of a family with Li-Fraumeni syndrome

Hunter Colegrove, Marianne E. Dubard-Gault, Henry Marshall, Brendan F. Kohrn, Thomas Horace Smith, Zachary K. Norgaard, Fang Yin Lo, Elizabeth K. Schmidt, Jacob E. Higgins, Charles C. Valentine, Desiree A. Marshall, John I. Clark, Eric Quentin Konnick, Jesse J. Salk, Marshall S. Horwitz, , Rosa Ana Risques

Duplex sequencing of a Li-Fraumeni family links germline TP53 p.R181H to higher neutral-region mutagenesis and weaker blood TP53 selection, plus recurrent p.R248Q/W hits across proband tissues.

bioRxiv · Aug 20, 2026 · PreprintCancer Biology✦ In-depth digest

Genetic and functional characterization of inherited complex chromosomal rearrangements in a family with multisystem anomalies

He Fang, Stephen M. Eacker, Yu Wu, Whitney Neufeld‐Kaiser, Mercy Laurino, Sioḃán Keel, Marshall S. Horwitz, Yajuan J. Liu

The paper characterizes an inherited complex chromosomal rearrangement in a family with multisystem anomalies using multiple genomic and functional analyses.

Genetics in Medicine Open · Jan 1, 2025Peer-reviewedGenetic & Genomic Medicine

Simultaneous Identification of Brain Cell Type and Lineage via Single Cell RNA Sequencing

Donovan J. Anderson, Florian M. Pauler, Aaron McKenna, Jay Shendure, Simon Hippenmeyer, Marshall S. Horwitz

The paper uses scRNA-seq data from mouse brain cortex to identify cell types and lineages by analyzing LOH events and gene expression patterns.

bioRxiv · Dec 31, 2020 · PreprintGenomics