Author

Juho M. Jalkanen

University of TurkuORCID 0000-0002-1693-8293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Eloi SchmauchiD· 2 shared Hannu J. KokkiiD· 2 shared Jari HaloneniD· 2 shared Jarmo M. GunniD· 2 shared Johannes Ojanen· 2 shared Juha E.K. HartikaineniD· 2 shared Kristiina Harju· 2 shared Kyriaki Galani· 2 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Eloi SchmauchORCID

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2 papers

Recent·Most cited

QClus: A droplet-filtering algorithm for enhanced snRNA-seq data quality in challenging samples

Eloi Schmauch, Johannes Ojanen, Kyriaki Galani, Juho M. Jalkanen, Kristiina Harju, Maija Hollmén, Hannu J. Kokki, Jarmo M. Gunn, Jari Halonen, Juha E.K. Hartikainen, Tuomas Kiviniemi, Pasi Tavi, Minna Unelma Kaikkonen, M Kellis, Suvi Linna-Kuosmanen

QClus improves snRNA-seq data quality by filtering droplets in challenging samples, achieving high quality across multiple datasets and metrics.

Nucleic Acids Research · Nov 4, 2024Peer-reviewedGenomics

Cardiovascular disease causes proinflammatory microvascular changes in the human right atrium

Suvi Linna-Kuosmanen, Eloi Schmauch, Kyriaki Galani, Johannes Ojanen, Carles A. Boix, Tiit Örd, Anu Toropainen, Prosanta Singha, Pierre R. Moreau, Kristiina Harju, Adriana Blazeski, Åsa Segerstolpe, Veikko Lahtinen, Lei Hou, Kai Kang, , M Kellis

The paper uses single-nuclei RNA-seq and spatial transcriptomics to analyze gene expression changes in the right atrium of patients with ischemic heart disease, revealing inflammatory microvascular dysfunction and altered tissue composition.

Cell Reports Medicine · May 1, 2024Peer-reviewedMolecular Biology