Izabela Horvath

LipiGo: A Versatile DNA-Lipid Nanoparticle Hybrid for Precision Drug Delivery

LipiGo is a DNA-lipid nanoparticle hybrid that enables efficient delivery of functional mRNA to non-hepatic tissues, particularly the spleen, through passive redistribution and active targeting.

Deep Learning and 3D Imaging Reveal Whole-Body Alterations in Obesity

This paper introduces MouseMapper, a deep learning tool combined with 3D imaging to analyze whole-body structural changes in obesity, revealing nerve and immune system alterations.

Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution

The paper identifies cellular sources of PET signals in glioblastoma by combining radiotracer uptake with 3D-histology and proteomics, showing tumor cells mainly contribute to TSPO enrichment while TAMs have specific PET targets.

SARS-CoV-2 Spike Protein Accumulation in the Skull-Meninges-Brain Axis: Potential Implications for Long-Term Neurological Complications in post-COVID-19

This study shows SARS-CoV-2 spike protein accumulates in the skull-meninges-brain axis, causing brain cell death and long-term neurological effects.