Author

Xiaofei Yu

Fudan UniversityORCID 0000-0002-1712-331XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Aldana M. AntoniazziiD· 1 shared Chris B. SchafferiD· 1 shared Conor M. ListoniD· 1 shared Edward K. FungiD· 1 shared Gang WangiD· 1 shared George VaiseyiD· 1 shared Gholamreza HassanzadehiD· 1 shared GuoQiang CheniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperNeuroscience

Aldana M. AntoniazziORCID

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3 papers

Recent·Most cited

Mediator subunit MED16 cooperates with UBP1-TFCP2 to control the promoter context-dependent transcriptional activity

Yuan-Ming Zheng, Xiaying Zhao, Ming Yang, Xinyi Yang, Huanzhang Zhu, Xiaofei Yu, Qiang Zhou, Gang Wang

This study identifies MED16-UBP1 as a regulatory module with dual transcriptional activity, showing both activation of silenced genes and repression of HIV-1 transcription.

bioRxiv · Aug 12, 2025 · PreprintBiochemistry

Bidirectional Regulation of Motor Circuits Using Magnetogenetic Gene Therapy

Santiago René Unda, Lisa E. Pomeranz, Roberta Marongiu, Xiaofei Yu, Leah Kelly, Gholamreza Hassanzadeh, Henrik Molina, George Vaisey, Putianqi Wang, Jonathan P. Dyke, Edward K. Fung, Logan Grosenick, Rick T. Zirkel, Aldana M. Antoniazzi, Sofya Norman, , Michael G. Kaplitt

This paper develops magnetogenetic tools to bidirectionally regulate specific neuronal circuits in vivo using magnetic fields and shows their efficacy in motor control and Parkinson's models.

Science Advances · Oct 9, 2024Peer-reviewedNeuroscience

Spatial Meta-transcriptomes of human and murine intestines

Lin Lv, Ru Feng, Xue Li, Xiaofei Yu, GuoQiang Chen, Lei Chen

The paper develops a pipeline to analyze spatial transcriptomic data for microbial sequences, validates it on human and murine intestinal datasets, and presents initial biological insights.

bioRxiv · Dec 13, 2021 · PreprintSystems Biology