Non-invasive in vivo bidirectional magnetogenetic modulation of pain circuits.
Aldana M. Antoniazzi, Santiago René Unda, Sofya Norman, Lisa E. Pomeranz, Roberta Marongiu, Sarah A. Stanley, Jeffrey M. Friedman, Michael G. Kaplitt
This paper introduces a magnetogenetic method to bidirectionally control pain circuits in mice using magnetic fields and a fusion protein, showing both excitatory and inhibitory effects on nociceptor activity.
bioRxiv · Mar 18, 2025 · PreprintNeuroscience