Henrik Molina

Brig3, a DNA glycosylase from a soil metagenome, excises 5-hydroxymethylcytosine from T-even phage DNA; the glucose hydrolase BapA extends defense to glucosylated genomes such as wild-type T4.

This study compares transcriptome and proteome profiles of three microglia sources, identifying shared surface markers and HERV expression patterns, suggesting MDMi as a practical model for functional studies.

This study identifies KMT2E as a reader of H3K4me3Q5ser, showing its role in regulating chromatin dynamics and neurodevelopmental gene expression in ODLURO syndrome.

This study shows that macronutrient composition and genetic background influence the response to a ketogenic diet in mice, with B6J mice losing weight on a low-protein KD due to increased GDF15 and LCN2 levels.

The paper identifies divergent mitochondrial and metabolic profiles between ALS-vulnerable and resilient neurons, revealing how these differences contribute to selective vulnerability in ALS.

This study identifies genotype-specific mitochondrial metabolic vulnerabilities in liver cancer and shows that phosphatidylethanolamine synthesis contributes to immune evasion.

The paper identifies ZZEF1 as a tRNA-specific transcription factor that suppresses breast cancer metastasis by regulating tRNA-LysUUU expression and affecting codon-specific translation.

The paper identifies DHRS3 as a lipid droplet protein that regulates melanoma cell state by modulating retinoid signaling.

This paper develops magnetogenetic tools to bidirectionally regulate specific neuronal circuits in vivo using magnetic fields and shows their efficacy in motor control and Parkinson's models.

The paper identifies dopaminylated proteins in the brain, including γCaMKII, and shows its role in synaptic-to-nuclear signaling and memory formation.

This study identifies two rapidly evolving genes in Aedes aegypti mosquitoes that enable extended egg retention during drought, enhancing reproductive resilience.

A single enzyme, TGM2, bidirectionally controls H3 monoaminylation dynamics, which, in turn, facilitate neural rhythmicity.

The paper shows oxidative stress causes tyrosine tRNA fragmentation, leading to translational repression and growth suppression through depletion of the precursor tRNA and inhibition of transcript destabilization.

This paper identifies GPR151 as a critical modulator of habenular function that controls addiction vulnerability across different drug classes.

The paper identifies TARBP2 as a nuclear RNA-binding protein that regulates transcript stability through m6A methylation, splicing inhibition, and exosome-mediated degradation, with implications for lung cancer progression.

The paper identifies a neuropeptide system in Aedes aegypti mosquitoes that enforces paternity by preventing remating and ensuring sperm from the first male fertilizes all offspring.