Gregory C. Miller

This study shows that mRNA-LNPs can efficiently deliver mRNA to hepatocytes in healthy and diseased livers, including tumors, suggesting potential for systemic mRNA therapy in liver cancer.

This study shows that myeloid HDAC7 promotes liver inflammation and glucose dysregulation in obesity, using mouse models and human data.

This study shows that CASP1 self-cleavage terminates its activity in vivo, maintaining homeostasis and preventing inflammasome-driven diseases.

This paper tests whether perisurgical CSF1 treatment reduces liver I/R injury in rats by enhancing macrophage activity and liver regeneration.