Author

Andrew Donald Clouston

The University of QueenslandORCID 0000-0002-9601-7952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Quan Hoang NguyeniD· 3 shared Zherui XiongiD· 3 shared Elizabeth Ellen PowelliD· 2 shared Gregory C. MilleriD· 2 shared Kate SchroderiD· 2 shared Katharine M. IrvineiD· 2 shared Sabrina Sofia BurgeneriD· 2 shared Andrew CauseriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

Quan Hoang NguyenORCID

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3 papers

Recent·Most cited

Myeloid HDAC7 drives liver inflammation and systemic glucose dysregulation during diet-induced obesity

Yizhuo Wang, Divya Ramnath, Kaustav Das Gupta, P. Prakrithi, Kavita Bisht, Gregory C. Miller, Zherui Xiong, Yujun Wan, Ellen N. Tejo, James E. B. Curson, Rishika Abrol, Sahar Keshvari, Kimberley S. Gunther, Jordan D. Atkinson, Zhixuan Loh, , Denuja Karunakaran

This study shows that myeloid HDAC7 promotes liver inflammation and glucose dysregulation in obesity, using mouse models and human data.

Clinical & Translational Immunology · May 29, 2026Peer-reviewedImmunology

Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseases

Sabrina Sofia Burgener, Mark Thomas Milner, Shoumit Dey, Pooranee K. Morgan, Daniel G. Blackmore, Emmanuelle Frampton, Gregory C. Miller, Monalisa Duarte de Oliveira, Kirsten Myra Kenney, Rinie Bajracharya, Ulrich Baumgartner, Thomas J. C. Collins, Zherui Xiong, Quan Hoang Nguyen, Peter J. Meikle, , Kate Schroder

This study shows that CASP1 self-cleavage terminates its activity in vivo, maintaining homeostasis and preventing inflammasome-driven diseases.

bioRxiv · Apr 28, 2025 · PreprintImmunology

Spatial Transcriptomic Signature of Progressive Fibrosis in Human MASLD: Role of Senescence and Metabolic Reprogramming.

Hani Vu, Yuliangzi Sun, Zherui Xiong, Daniel E. Radford‐Smith, Andrew Causer, Christian Maximilian Nefzger, Eoin Daniel O'Sullivan, Matthew J. Watt, Grant A. Ramm, Andrew Donald Clouston, Katharine M. Irvine, Quan Hoang Nguyen, Elizabeth Ellen Powell

This study uses spatial transcriptomics to analyze liver fibrosis stages in MASLD, identifying metabolic reprogramming and senescence signatures linked to fibrosis progression.

bioRxiv · Mar 20, 2025 · PreprintGenomics