Maryam Moarefian

Spatially defined axonal guidance in neural organoids with micropatterned microfluidic channels

This paper introduces a microfluidic platform called directoids to study directional axonal growth between neural organoids, showing robust directional bias in axon outgrowth.

A Modular In-Incubator Microscope for Longitudinal Live Cell Microscopy

This paper introduces an automated in-incubator microscope for long-term live cell imaging, enabling high-frequency, continuous data collection with improved thermal stability and operational reliability.

Incubator-Free Organoid Culture in a Sealed Recirculatory System

This paper introduces a sealed recirculatory system for organoid culture that eliminates the need for CO2 incubators and enables continuous live imaging and metabolic viability.

Calcium dynamics tune timing of developmental transitions to generate evolutionarily divergent axon tract lengths

The paper shows that slower axon growth in humans, driven by reduced calcium influx, leads to longer axon tracts through prolonged growth duration, with calcium dynamics regulating developmental timing.