Author

Natasha Mahealani Flores

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-1917-0507Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Pawel Karol MazuriD· 3 shared Jinkai WaniD· 2 shared Lingnan Ren· 2 shared Simone HausmanniD· 2 shared Tourkian ChasaniD· 2 shared Anne‐Emmanuelle FoucheriD· 1 shared Benjamin ZimaniD· 1 shared Bin XiangiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

Pawel Karol MazurORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

KDM7B-mediated demethylation of RNF113A regulates small cell lung cancer sensitivity to alkylation damage

Tanveer Ahmad, Xiaojie Yang, Anne‐Emmanuelle Foucher, Lingnan Ren, Ning Tsao, Natasha Mahealani Flores, Jinkai Wan, Lucid Belmudes, Etienne Dubiez, Monika Chandan Bhowmik, Jessica Vayr, Simone Hausmann, Florent Chuffart, Xiaoyin Lu, Sandrine Blanchet, , Nicolas Reynoird

This study identifies KDM7B as a demethylase that regulates RNF113A, affecting DNA repair and chemoresistance in small cell lung cancer.

bioRxiv · Jan 3, 2026 · PreprintCell Biology

SETD2 suppresses tumorigenesis in a KRASG12C-driven lung cancer model and its catalytic activity is regulated by histone acetylation

Ricardo J Mack, Natasha Mahealani Flores, Geoffrey Fox, Hanyang Dong, Metehan Cebeci, Simone Hausmann, Tourkian Chasan, Jill M. Dowen, Brian D. Strahl, Pawel Karol Mazur, Or Gozani

This study shows SETD2 suppresses lung cancer in a KRASG12C model and its activity is regulated by histone acetylation and ubiquitination.

eLife · Sep 15, 2025Peer-reviewedMolecular Biology

Planarians Develop Radiotolerance to Recurrent Ionizing Radiation Exposure

Paul G. Barghouth, Benjamin Ziman, Eli Isael Maciel, Peter Karabinis, Salvador Rojas, Natasha Mahealani Flores, Edelweiss Pfister, Néstor J. Oviedo

This study shows planarians develop radiotolerance through repeated ionizing radiation exposure, maintaining genomic integrity and reproductive function.

bioRxiv · Oct 25, 2024 · PreprintDevelopmental Biology

SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma

Bisi Miao, Ling Ge, Chenxi He, Xinghao Wang, Jibo Wu, Xiang Li, Kun Chen, Jinkai Wan, Shenghui Xing, Lingnan Ren, Zhennan Shi, Shengnan Liu, Yajun Hu, Jiajia Chen, Yanyan Yu, , Fei Lan

This study identifies SMYD5 as a methyltransferase that modifies RPL40 K22me3, enhancing translation and promoting hepatocellular carcinoma.

Cell Research · Aug 5, 2024Peer-reviewedCancer Biology