Catherine Vénien‐Bryan

Structural insights into the inactive state of the adhesion GPCR ADGRV1

This study presents the cryo-EM structure of inactive ADGRV1 and shows it has weak constitutive activation and an alternative activation mechanism distinct from other aGPCRs.

Structure of the human KEOPS/tRNA complex and characterization of pathogenic variants responsible for the Galloway Mowat syndrome.

The paper determines the structure of the human KEOPS/tRNA complex and characterizes pathogenic variants in the t6A pathway linked to Galloway-Mowat syndrome.

Biochemical, biophysical, and structural investigations of two mutants (C154Y and R312H) of the human Kir2.1 channel involved in the Andersen-Tawil syndrome.

This study investigates two Kir2.1 mutants linked to Andersen-Tawil syndrome, showing they impair channel function through distinct mechanisms, with C154Y causing dominant-negative effects.

Endocannabinoid regulation of inward rectifier potassium (Kir) channels

This study investigates how endocannabinoids modulate Kir2.1 channel function independently of cannabinoid receptors, revealing differences in their effects on related Kir channels.