Werner Kühlbrandt

Structures of Chaetomium thermophilum TOM complexes with bound preproteins

The paper presents four structures of the TOM complex from Chaetomium thermophilum, showing its interaction with preproteins and revealing dynamic receptor conformations.

In situ structure and rotary states of mitochondrial ATP synthase in whole cells

The paper determines the in situ structure of mitochondrial ATP synthase in Polytomella algae using electron cryo-tomography, revealing six rotary positions and 21 substates of the F1 head.

Structure and autoregulation of a P4-ATPase lipid flippase

The paper determines the structures of the P4-ATPase Drs2p-Cdc50p using cryo-EM, revealing autoinhibition and PI4P-dependent activation mechanisms.