Author

Nicholas L. Mervosh

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 3

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Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Drew D. KiralyiD· 3 shared Ana Nicolle StratiD· 2 shared Katherine R. MeckeliD· 2 shared Tanner J. EustoniD· 2 shared Amon T. Orr· 1 shared Ariela Buxbaum Grice· 1 shared Aya OsmaniD· 1 shared Catherine J. PeñaiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Drew D. KiralyORCID

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3 papers

Recent·Most cited

Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice

Aya Osman, Nicholas L. Mervosh, Ana Nicolle Strat, Tanner J. Euston, Gillian Zipursky, Rebecca M. Pollak, Katherine R. Meckel, Scott R. Tyler, Kenny L. Chan, Ariela Buxbaum Grice, Elodie Drapeau, Lev Litichevskiy, Jasleen Gill, Sharon M. Zeldin, Christoph A. Thaiss, , Drew D. Kiraly

The paper shows acetate supplementation improves social deficits and changes gene expression in the prefrontal cortex of Shank3-deficient mice.

Brain, Behavior, and Immunity · Nov 1, 2023Peer-reviewedNeuroscience

The gut microbiome and its metabolites are necessary for morphine reward

Rebecca S. Hofford, Nicholas L. Mervosh, Tanner J. Euston, Katherine R. Meckel, Amon T. Orr, Drew D. Kiraly

This study shows that gut microbiome depletion reduces morphine reward and that short-chain fatty acids mediate this effect through changes in nucleus accumbens gene expression.

bioRxiv · Sep 17, 2020 · PreprintNeuroscience

Multi-OMIC analysis of brain and serum from chronically-stressed mice reveals network disruptions in purine metabolism, fatty acid beta-oxidation, and antioxidant activity that are reversed by antidepressant treatment

Peter J. Hamilton, Emily Y. Chen, Vladimir Tolstikov, Catherine J. Peña, Punit Shah, Kiki Panagopoulos, Ana Nicolle Strat, Deena M. Walker, Zachary S. Lorsch, Nicholas L. Mervosh, Drew D. Kiraly, Rangaprasad Sarangarajan, Niven R. Narain, Michael A. Kiebish, Eric J. Nestler

The paper analyzes multi-omic data from stressed mice to identify molecular disruptions linked to depression and shows antidepressants reverse these changes in specific brain regions.

bioRxiv · Dec 8, 2018 · PreprintNeuroscience