Author

Ariana Arce

The University of Texas Southwestern Medical CenterORCID 0009-0006-8602-686XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Bret M. EversiD· 1 shared Cheryl M. LewisiD· 1 shared Chul Woo AhniD· 1 shared Emily SteiniD· 1 shared Esra A. AkbayiD· 1 shared Guoqiang LiuiD· 1 shared Ignacio Ivan WistubaiD· 1 shared Jing Hui YangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Bret M. EversORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 18, 2025

CDH3 as a Novel Therapeutic Target in Basal-like Double-Negative Prostate Cancer

Guoqiang Liu, Shiyu Wang, Loan Duong…·Xin Lü

This study identifies CDH3 as a key driver of basal-like prostate cancer and shows that CDH3-targeted therapies like ADCs and CAR T cells are effective in preclinical models.

DOI 10.1101/2025.11.18.689150

mousebulk RNA-seq

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Cancer BiologyCancer ResearchPeer-reviewedMay 6, 2025

Coordinated translational control of multiple immune checkpoints by the integrated stress response pathway in lung cancer

Shayna Elizabeth Thomas-Jardin, Shruthy Suresh, Ariana Arce…·Kathryn A. O’Donnell

The paper shows that the integrated stress response (ISR) coordinates the translation of PD-L1 and CD155, two immune checkpoint proteins, in lung cancer, and suggests combining ISR inhibition with PD-1 blockade as a therapeutic strategy.

13 citationstop 4%

humanbulk RNA-seq

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