Shiyu Wang

The paper introduces GLOM-TGITO, a method for protein design that combines multiscale modeling with multiview landscape-guided optimization, achieving high accuracy and novel sequence discovery.

This paper develops engineered dendritic cell-derived small extracellular vesicles that combine T-cell priming with checkpoint reprogramming to enhance antitumor immunity.

This study identifies CDH3 as a key driver of basal-like prostate cancer and shows that CDH3-targeted therapies like ADCs and CAR T cells are effective in preclinical models.