Author

Liang Cheng C

Brown UniversityORCID 0000-0001-6049-5293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Adriana Morales MirandaiD· 1 shared Ariana ArceiD· 1 shared Bin ZhuiD· 1 shared Guoqiang LiuiD· 1 shared Haoyu ZhangiD· 1 shared Jacob WilliamsiD· 1 shared Jing Hui YangiD· 1 shared Joycelyn Williams· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Adriana Morales MirandaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 18, 2025

CDH3 as a Novel Therapeutic Target in Basal-like Double-Negative Prostate Cancer

Guoqiang Liu, Shiyu Wang, Loan Duong…·Xin Lü

This study identifies CDH3 as a key driver of basal-like prostate cancer and shows that CDH3-targeted therapies like ADCs and CAR T cells are effective in preclinical models.

DOI 10.1101/2025.11.18.689150

mousebulk RNA-seq

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GenomicsbioRxivPreprintJun 12, 2025

A Thiopurine-like Mutagenic Process Defines TGCT Subtypes

Kevin M. Brown, Jun Zhong, Adriana Morales Miranda…·Tongwu Zhang

This study identifies a unique mutational signature, SBS87, in testicular germ cell tumors (TGCTs) that resembles thiopurine-induced DNA damage and is associated with tumor latency and telomere elongation.

1 citation

humanwhole-genome sequencing

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