Rebecca A. Siwicki

The paper screens 2,707 compounds in human retinal organoids to identify those that protect or damage cone photoreceptors, finding CK1 and MAPK11 inhibitors as protective.

The paper improves the FLASH-seq protocol for long-read scRNA-seq on ONT, develops barcoding strategies, and presents a bioinformatics pipeline, while highlighting technical challenges.

This study uses explanted SEEG electrodes to integrate RNA sequencing, DNA methylation, and genomic data with electrophysiological recordings, revealing distinct molecular landscapes in epilepsies and identifying potential seizure zones.

This study integrates metabolomics and RNAseq from the same liver samples to show that prior metabolite extraction does not harm RNAseq quality and reveals pyrimidine metabolism as a key pathway in acute viral infection.

STORM-seq improves single-cell RNA sequencing by enhancing detection of non-coding transcripts and transcript-level complexity, revealing new cell states in human fallopian tube epithelium.