Author

Arun Mahesh

University of Southern Denmark

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Assay:electronic health records· 1

Frequent Co-Authors

Albert SanfeliuiD· 3 shared David Clifford HenshalliD· 3 shared Vijay Kumar TiwariiD· 3 shared Julian Larkin· 2 shared Peter Widdess‐WalshiD· 2 shared Anuj Kumar DwivediiD· 1 shared Anuj Kumar Dwiwedi· 1 shared Donncha F. O’Brien· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Albert SanfeliuORCID

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3 papers

Recent·Most cited

Transcriptomic profiles from stereo-EEGs reveal the local cell microenvironment in human epilepsy

Julian Larkin, Anuj Kumar Dwivedi, Arun Mahesh, Albert Sanfeliu, Vijay Kumar Tiwari, Peter Widdess‐Walsh, David Clifford Henshall

The paper uses transcriptomic data from SEEG electrodes to characterize the molecular microenvironment in human epilepsy, showing gene expression reflects local brain activity and cell types.

bioRxiv · Sep 16, 2025 · PreprintNeuroscience

High-Resolution Multimodal Profiling of Human Epileptic Brain Activity via Explanted Depth Electrodes

Anuj Kumar Dwiwedi, Arun Mahesh, Albert Sanfeliu, Julian Larkin, Rebecca A. Siwicki, Kieron J. Sweeney, Donncha F. O’Brien, Peter Widdess‐Walsh, Simone Picelli, David Clifford Henshall, Vijay Kumar Tiwari

This study uses explanted SEEG electrodes to integrate RNA sequencing, DNA methylation, and genomic data with electrophysiological recordings, revealing distinct molecular landscapes in epilepsies and identifying potential seizure zones.

bioRxiv · Jul 3, 2024 · PreprintGenomics

MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control

Mona Heiland, Niamh M. C. Connolly, Omar Mamad, Thanh Ngoc Nguyen, Jaideep Kesavan, Elena Langa, Kevin Fanning, Albert Sanfeliu, Yan Yan, Junyi Su, Morten Trillingsgaard Venø, Lara S. Costard, Valentin Neubert, Tobías Engel, Thomas D. M. Hill, , David Clifford Henshall

This study identifies miR-335-5p as a regulator of voltage-gated sodium channels, showing that its modulation can influence seizure activity in epilepsy models.

Proceedings of the National Academy of Sciences · Jul 18, 2023Peer-reviewedNeuroscience